Covid Vaccine Clinical Trials – Overview
Scientists are no less than gods to humans, especially during these crucial times of an ongoing pandemic. Scientists have learned a lot from the research and clinical trials of previous vaccines from different laboratories and companies.
Covid vaccine clinical trials brought us the life-saving vaccines to fight against the deadliest coronavirus.
The Covid vaccine clinical trials were performed on thousands of volunteers from different age groups.
The research institutes have conducted different phases of trials from different regions throughout the past two years. Interestingly, the clinical trials are still going on as new coronavirus variants are coming.
According to a recent study, the previous vaccines that were produced by companies were found ineffective against the new coronavirus variants.
Yes, the current vaccine is not much effective to fight against the new variants of Coronavirus and for that reason, the companies have started their research program on developing new vaccines to give protection against all the variants of this virus.
If we talk about the people who got vaccinated already, the numbers are in millions. Yes, hundreds of millions of people got vaccinated with two doses of Coronavirus vaccines approved by the authority. The current vaccine is quite effective against the previous version of Coronavirus but not good on the newly introduced variant i.e. Omicron.
AstraZeneca, Pfizer, Moderna, and many other companies have approved their Coronavirus vaccines. The world is using the vaccines produced by these companies as they have proved to be the most effective vaccines against the Coronavirus.
Now, the same companies are providing a special booster shot or booster dose to provide extra protection against the newly introduced Coronavirus variant.
How Do Covid Vaccine Clinical Trials Work?
Covid Vaccine Clinical Trials is a process to pass the newly invented vaccines to prevent the spread of the coronavirus. Basically, it’s a medical, clinical trial procedure where the vaccines will be given to volunteers.
Yes, volunteers who have given permissions for clinical trials of Covid Vaccines will be the first ones to test out the vaccine. The research team will examine the effects of the Covid vaccines on the volunteers.
The clinical trial phase comes after thorough research by the scientists in the laboratory. Once the research team approved the vaccine or the medicine to use on people, the company will then start the clinical trials on volunteers.
After collecting the data from the volunteers, the company will then prepare their documentation for approval of their new vaccine or drug to IRB and FDA.
The department will go through the trial data conducted by the team in different phases. If they found, the data is accurate and good for public use, the department will then approve the vaccine.
Is Covid Vaccine Clinical Trials Safe?
If you are wondering about whether should I become a volunteer for the covid vaccine trial, then let us make things clear for you. Your safety will be on the priority list during the clinical trials.
The clinical trial team will be monitoring the participants continuously throughout the testing phase. After all, it is a crucial part of the clinical trial and the research team must keep the safety of their volunteers in the front.
What’s the Procedure for Volunteers for Covid Vaccine?
Not just Covid Vaccine’s Clinical Trial, but the clinical trial procedure is the same for all the other drugs, medicines, and vaccines. The procedure takes place in different phases which means the company must collect the data from all the phases to prepare the documents for final approval.
Before they begin testing their new vaccine or drug, they must take approval from the Institutional Review Board i.e. IRB. The IRB is a group of scientists, doctors, researchers, and people like us to make sure that the medicines are good and will not put the volunteers at risk.
The IRB has well-experienced members from different professions so that they can share their opinions about the new medicines/ vaccines.
Some clinical trials of medicines are monitored by DSMB i.e. Data and Safety Monitoring Board. The DSMB consists of professionals who keep on checking the results of different clinical trials periodically.
They are the responsible ones to take the final decision if the process is not going well or if the medicine is harming the volunteers. They have the authority to stop the Clinical Trial process anytime.
Volunteers must fill in the consent form to permit them to try out the new Covid Vaccine. The consent form describes everything about the present and post effects of the vaccine. It also describes the side effects of the drug or the vaccine.
The Latest Covid Vaccine Clinical Trial Process
Pfizer and BioTech are testing the fourth dose of their Covid Vaccine. The company has already launched and got approved its three vaccines along with the booster dose. And now, they are preparing for the launch of their new i.e. fourth Covid vaccine.
The latest Covid Vaccine Clinical Trials is for the new variant of coronavirus i.e. Omicron. Yes, Pfizer and BioTech are now working on a new vaccine to fight against the Omicron-based virus in humans.
The company has already begun the Clinical Trials on those who have taken the booster dose i.e. the third dose of the Covid 19 vaccine up to six months earlier. The same covid 19 clinical trials are conducted on those who didn’t receive any vaccine dose yet.
This will make things much clearer for both types of patients, those who have taken all the doses of the vaccine and those who haven’t taken a single dose of the vaccine yet.
The Covid Vaccine Clinical Trials for the fourth vaccine will also be trialed on those who have taken a single dose and a double dose of the vaccines. The clinical trial will be conducted on all types of users.
However, they aim to focus on those who have taken the third dose of the vaccine. The company believes that those who have taken all three doses of their vaccines will be recovered faster.
The new Omicron variant will not affect much on those who have taken their three doses of vaccines including the booster dose.
However, more information about the fourth dose of the vaccine will be revealed only after successful testing and clinical trials which will take a few more weeks.
About the Omicron Variant
The Omicron Variant is the latest variant of Coronavirus after the Delta variant. Yes, the Delta variant has been replaced by the Omicron and this variant is now spreading like a wildfire across the globe.
This variant is split into its different forms as many countries have found the different forms of Omicrons which is a serious matter for the scientists and the research teams.