5 Best Obesity Clinical Trials of 2023

Best Obesity Clinical Trials – Overview

Obesity is one of the most prevalent health risks that endanger the health and well-being of adults and children in the United States. According to several studies, every state today has an obesity rate of more than 20%. The states in the South and Midwest have the highest prevalence of obesity, at 34.1%.

Obesity-related conditions, such as heart disease, stroke, type-2 diabetes, and certain types of cancers, are on the rise and have become the leading cause of premature death in the US. In addition, the estimated medical cost for treating an adult for obesity is around US $1,860 more than for those with a normal weight range.

Scientists and scholars have been studying this phenomenon for years and have organized numerous types of obesity clinical trials. These trials are established to find better and more efficient ways to curb the obesity pandemic gripping the United States.

Top 5 Obesity Clinical Trials of 2023

In this article, we have listed the top obesity clinical trials in the US in 2023.

1 – Regulation of Muscle Protein Phenotype in Humans with Obesity

This study aims to determine the turnover rate of motor protein isoforms and overall muscle protein in the skeletal muscles of people with obesity. The study also aims to research lean controls in the basal state and determine the stimulation of the turnover rate of motor protein in the skeletal muscle of subjects with obesity. The study is set to check lean controls by plasma amino acids, with and without prior exercise.

The eligibility criteria for participating in this obesity clinical trial include restrictions on age, gender, type, and stage of disease, along with previous health treatments or health problems. The rules differ from study to study and aim to identify who can or cannot be part of this obesity clinical trial.

To know more, you can contact the study team and discuss eligibility and potential participation at [email protected].

2 – Changes in Gut Microbiota after Placement of Endoscopic Intragastric Balloon

The study aims to find the relation between changes in the gut microbiome of obese persons undergoing intragastric balloon procedures.

The eligibility criteria for participation in this obesity clinical trial require applicants to be over the age of 18 years. In addition, the participant should also be a Mayo Clinic patient who has chosen to undergo an intragastric balloon procedure clinically or as part of the research trial.

You can visit the official website to learn more details about the eligibility criteria and participation process.

3 – Study to Evaluate Endoflip Normal Ranges Data in Healthy Volunteers

This study aims to find the normal range of diameter and distensibility of the pylorus and the fasting and post-prandial antro-pyloric motility in healthy male and female adults.

The eligibility criteria for participating in this obesity clinical trial require the applicants to be either male or female, between 18 and 65 years old, and have a body mass index (BMI) between 18 and 35 kg/m².

However, the exclusion criteria bars applicants suffering from regurgitation, heartburn, or symptoms of gastroparesis, such as early satiety, nausea, post-prandial bloating, and upper abdominal pain, or if the applicant is pregnant.

To learn more details about eligibility criteria and the application process for this obesity clinical trial, you can contact the principal investigator directly at https://www.mayo.edu/research/faculty/camilleri-michael-m-d-d-sc/bio-00026245.

4 – Intragastric Balloon in Obese Adolescents with Comorbidities

This study aims to find more information about the effectiveness and safety of using an ORBERA Intragastric Balloon. In addition, the study aims to learn if older teenagers who suffer from obesity will lose weight and if their medical problems related to obesity will get better.

The FDA currently approves ORBERA for overweight adults and the study wants to find its feasibility for use in overweight older teenagers. The participation criteria for this obesity clinical trial include limits on gender, age, type, and stage of disease, along with any previous health concerns and treatments.

For instance, the trial expects the ideal participant to have a BMI of over 35 or 40 kg/m², along with one or more comorbidities, such as type-2 diabetes, sleep apnea, pseudo motor cerebri, hypertension, NASH, etc.

You can find more details of the eligibility criteria and the application process for this clinical trial by emailing the contact at [email protected].

5 – Quality of Life after Simultaneous Sleeve Gastrectomy and Liver Transplantation

This study aims to check the quality of life among several obese liver transplant recipients and compare the results between those who underwent sleeve gastrectomy and those who did not.

The eligibility criteria for this obesity clinical trial require participants to have undergone liver transplants with pre-transplant medically complicated obesity and who have gone through LT or LT+SG within the study period.

To find more details about the eligibility criteria and the application process for this obesity clinical trial, we advise you to contact the principal investigator directly at https://www.mayo.edu/research/faculty/heimbach-julie-k-m-d/bio-00085814.

Conclusion

These are the top 5 obesity clinical trials in the US in 2023. Make sure to visit the investigator’s official website to find specific eligibility criteria and the process to apply for participating in any of these obesity clinical studies.

Your contribution may help determine better and more efficient treatments for different obesity-related health and lifestyle problems.

References

https://www.cdc.gov/obesity/data/adult.html

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