5 Best Obesity Clinical Trials - Grants for Medical

Best Obesity Clinical Trials – Overview

Obesity is one of the most prevalent health risks that endanger the health and well-being of adults and children in the United States. Recent studies show that all U.S. states have an obesity rate exceeding 20%, with the highest rates observed in the South and Midwest. However, specific obesity rates vary by state and can exceed 34.1% in certain areas.

Obesity-related conditions, such as heart disease, stroke, type-2 diabetes, and certain types of cancers, are on the rise and have become the leading cause of premature death in the US. In addition, the additional estimated annual medical cost for adults with obesity compared to those of normal weight is approximately $1,860 to $2,500 in the U.S..

Scientists and scholars have studied this phenomenon for years and organized numerous obesity clinical trials. These trials are established to find better and more efficient ways to curb the obesity pandemic gripping the United States.

Top 5 Obesity Clinical Trials

5 Obesity Clinical Trials

In this article, we have listed the top obesity clinical trials in the US.

1 – Regulation of Muscle Protein Phenotype in Humans with Obesity

This study aims to determine the turnover rate of motor protein isoforms and overall muscle protein in the skeletal muscles of people with obesity. The study also aims to research lean controls in the basal state and determine the stimulation of the turnover rate of motor protein in the skeletal muscle of obese subjects. The study is set to check lean controls by plasma amino acids, with and without prior exercise.

The eligibility criteria for participating in this obesity clinical trial include restrictions on age, gender, type, and stage of disease, along with previous health treatments or health problems. The rules differ from study to study and aim to identify who can or cannot be part of this obesity clinical trial.

For more information on eligibility and participation, interested individuals should refer to the clinical trial’s official contact details provided on its ClinicalTrials.gov entry or the sponsoring institution’s website.

2 – Changes in Gut Microbiota after Placement of Endoscopic Intragastric Balloon

The study aims to find the relation between changes in the gut microbiome of obese persons undergoing intragastric balloon procedures.

The eligibility criteria for participation in this obesity clinical trial require applicants to be over the age of 18 years. In addition, the participant should also be a Mayo Clinic patient who has chosen to undergo an intragastric balloon procedure clinically or as part of the research trial.

For detailed information on eligibility criteria and the participation process, prospective participants should consult the clinical trial listing on ClinicalTrials.gov or contact the study’s research team directly.

3 – Study to Evaluate Endoflip Normal Ranges Data in Healthy Volunteers

This study aims to find the normal range of diameter and distensibility of the pylorus and the fasting and post-prandial antro-pyloric motility in healthy male and female adults.

The eligibility criteria for participating in this obesity clinical trial require the applicants to be either male or female, between 18 and 65 years old and have a body mass index (BMI) between 18 and 35 kg/m².

However, the exclusion criteria bars applicants suffering from regurgitation, heartburn, or symptoms of gastroparesis, such as early satiety, nausea, post-prandial bloating, and upper abdominal pain, or if the applicant is pregnant.

To learn more details about eligibility criteria and the application process for this obesity clinical trial, you can contact the principal investigator directly at https://www.mayo.edu/research/faculty/camilleri-michael-m-d-d-sc/bio-00026245.

4 – Intragastric Balloon in Obese Adolescents with Comorbidities

This study aims to find more information about the effectiveness and safety of using an ORBERA Intragastric Balloon. In addition, the study aims to learn if older teenagers who suffer from obesity will lose weight and if their medical problems related to obesity will get better.

The FDA currently approves ORBERA for overweight adults and the study wants to find its feasibility for use in overweight older teenagers. The participation criteria for this obesity clinical trial include limits on gender, age, type, and stage of disease, along with any previous health concerns and treatments.

Eligibility for this trial includes individuals with a BMI of 35 kg/m² or higher, possibly with obesity-related comorbidities like type 2 diabetes, sleep apnea, pseudotumor cerebri, hypertension, or non-alcoholic steatohepatitis (NASH), among others.

You can find more details of the eligibility criteria and the application process for this clinical trial by emailing the contact at [email protected].

5 – Quality of Life after Simultaneous Sleeve Gastrectomy and Liver Transplantation

This study aims to check the quality of life among several obese liver transplant recipients and compare the results between those who underwent sleeve gastrectomy and those who did not.

The eligibility criteria for this obesity clinical trial require participants to have undergone liver transplants with pre-transplant medically complicated obesity and who have gone through LT or LT+SG within the study period.

To find more details about the eligibility criteria and the application process for this obesity clinical trial, we advise you to contact the principal investigator directly at https://www.mayo.edu/research/faculty/heimbach-julie-k-m-d/bio-00085814.

Conclusion

These are the top 5 obesity clinical trials in the US. Make sure to visit the investigator’s official website to find specific eligibility criteria and the application process for participating in any of these studies.

Your contribution may help determine better and more efficient treatments for different obesity-related health and lifestyle problems.