3 Most Recent Weight Loss Clinical Trials in US

Weight Loss Clinical Trials in the US

Obesity is one of the most prevalent health conditions affecting adults and children alike.

While those from some ethnicities are more prone to putting on weight easily, the overall statistics show that the problems are affecting the majority of the American population.

According to a report by the American Obesity Association (AOA) on obesity in America, around 42% of Americans in 2020 were obese while another 35% of adults are overweight.

This brings the number of obese in the US to an astonishing 120 million and it costs an estimated US$ 1.7 trillion in healthcare every year.

There have been intense research and studies conducted on the topic, to find out the triggering factors as well as discover the best and most effective way to lose unwanted, extra weight.

So, if you are looking to be part of weight-loss clinical trials, then you’ve come to the right place. In this article, we have listed some of the top sources that offer varying weight loss clinical trial opportunities.

Importance of Weight Loss Clinical Trials

Clinical trials are essential parts of clinical research and form the foundation of advances in medical science.

Clinical trials are ideal to discover new ways of preventing, diagnosing, and treating diseases.

Thousands of scientists across the US are currently engaged in various forms of clinical trials for weight loss and obesity.

While some studies are focused on the role of diet in the development and treatment of obesity, others are engaged in finding innovative and effective behavioral, surgical, medication and devices that can improve weight loss procedures.

Some of the major questions that scientists are attempting to answer by conducting weight-loss clinical trials include:

Identifying patients who may respond to a specific type of diet or drug,

Learning how bacteria in the gastrointestinal tract affects a person’s weight,

Studying how metabolism influences obesity and other similar health conditions,

Investigating the way a pregnant woman gains weight during pregnancy and how it can affect the mother’s health and the health of the baby as well,

Learning how physical activities improve and maintain a healthy weight limit.

Weight Loss Clinical Trials in the US

Now that you know how important these studies are, let’s take a quick look at some of the most prominent weight-loss clinical trials currently being conducted in the US:

1. Novel Executive Function Training for Obesity (NEXT)

The aim of the Novel Executive Function Training for Obesity (NEXT) program is to assist with the development of treatments, with two groups of 10 participants enrolled in a 12-week open-label treatment group.

Participants are expected to share qualitative feedback to help with treatment development.

Next, a randomized clinical trial will evaluate NEXT by comparing it with conventional BWL to check the feasibility, acceptability and preliminary efficacy.

Study type – Interventional (Clinical Trial)

Estimated enrolment – 64 participants

Allocation – Randomized

Intervention Model – Parallel Assignment

Masking – Single (Outcome Assessor)

Primary purpose – Treatment

Official title – Novel Executive Function Training for Obesity

2. Preventing Weight Gain Among Those Who Decline Behavioral Weight Loss Treatment (STEADY)

This trial is focused on discovering interventions that prescribe self-weighing but do not advise changes in diet or physical activity. This trial will investigate the feasibility and acceptability of this efficient self-weighing intervention to prepare a completely practical, randomized clinical trial.

The trial is focused on promoting regular self-weighing and the use of evidence-based weight management resources.

Study type – Interventional (Clinical Trial)

Estimated enrollment – 40 participants

Intervention model – Single Group Assessment

Intervention model description – Single-Arm Trial

Masking – None (Open Label)

Primary purpose – Prevention

Official title – Preventing Weight Gain Among Those Who Decline Behavioral Weight Loss Treatment

3. FRESH-TEEN: Families Responsibility Education Support Health for Teens

This clinical study will attempt to compare the efficiency of BWL and BWL+ER. Investigators will offer 6 months of treatment, including BWL+ER and BWL which will monitor the participants over 12 months post-treatment (total duration = 18 months).

The study will recruit adolescents who suffer from obesity or are overweight, along with their parents.

Parents and participants will eventually be assessed for anthropometry, emotional inhibition, emotional regulation, emotional eating and adolescent-parent relationship factors.

Study type – Interventional (Clinical Trials)

Estimated enrollment – 320 participants

Allocation – Randomized

Intervention model – Parallel Assignment

Masking – Single (Outcome Assessor)

Primary purpose – Treatment

Official title – Targeting Emotional Eating and Weight Loss in Adolescents

Conclusion

These are the top three weight-loss clinical trials to be conducted in the US soon.

If you are suffering from obesity, or are noticeably overweight, then it is highly recommended to visit the official website of the NIH and learn even more about any other weight-loss clinical trials in the US.

Reference links

https://www.prnewswire.com/

https://www.cdc.gov/obesity/data/adult.html

https://policylab.us/clinical-trials/weight-loss/

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