A new research project grant has been awarded by Marshall University. V. Pierre, Ph.D. who is an associate professor of biomedical sciences at the Marshall University Joan C. Edwards School of Medicine and interim director of the Marshall Institute for Interdisciplinary Research (MIIR) has been awarded a $1.36 million grant for the ongoing research program on kidney.
This particular research grant is the most competitive grant issued by the National Institutes of Health. It’s a four-year grant primarily focused on the management of salt by the kidneys. The grant has been released to study and improve the existing treatments on diabetes and digestive and other known kidney-related diseases.
The regulatory mechanism of a kidney to manage salt in a body and the malfunction due to unbalancing of salt in the body will be researched further through the newly awarded grant.
The Importance of a Kidney
We all know the importance of salt in our body and how our body removes an excessive amount of salt from the body. The imbalance of salt in our bodies causes kidney-related problems. If the amount is too high, then it may cause huge troubles in the body resulting in damage to the kidneys.
According to a recent study, over 40% of heart-related diseases are caused by the imbalance of salt in our body which is indirectly related to Kidneys.
The mishandling of salt balance by the body contributes to the development and progression of many common diseases, including hypertension and organ damage due to failure to remove excess amount of salt. Therefore, the proposed investigation has profound basic and clinical implications and may also provide new targets for developing better therapeutics.”
Sandrine V. Pierre, Ph.D., Associate Professor of Biomedical Sciences, Marshall University Joan C. Edwards School of Medicine
How the Research Study Will be Conducted?
As per the officials, Sandrine V. Pierre will begin her research project with a team of experienced researchers. The research study will be conducted in Joan C. Edwards School of Medicine. The team will be expertise in renal physiology and preclinical studies of Na/K-ATPase receptor function.
Researchers are researching new treatments that can reduce the impact of diabetes and other diseases so that they will not affect your kidneys. As per the recent survey, less than 20% of kidney-related patients are referred to Nephrologists.
The ongoing pandemic has affected the life of every single person on earth. The infected patients to Covid 19 have been provided different types of treatments with heavy doses of medicines. This can also affect the functionality of the Kidneys. The team will study all these subjects to know about the impact of medicines used by the doctors to cure the Covid 19 infection in patients.
Covid-19’s severe effect damages the myeloid cells and caused inflammation. Over 80% of Covid-19 infected patients with severe infection have lost their lives just because of Kidney or heart failure. This is what worries researchers across the globe.
Several groups have been actively working on the research program to find out the cause of spreading this virus. This will ultimately include the mechanism of the kidney and its changes due to Covid 19 infections.
About Sandrine V. Pierre
Sandrine V. Pierre is the leading researcher for a new project that will conduct a deep study on the mechanism of Kidneys to manage the salt imbalance and impact of Covid 19 on Kidneys. She joined Marshall University in 2014. If we talk about her qualification, she has a doctorate in cellular and molecular endocrinology from Aix-Marseille II University based in France.
She was working as a faculty at the University of Toledo College of Medicine before joining Marshall University. Her research project is based on the signaling function of the Na/K-ATPase. This project is all about studying the therapeutic applications of this signaling function in cardiovascular diseases. She received support from the American Heart Association and the National Heart, Lung, and Blood Institute.
About the Newly Announced R01 Grant
The R01 Grant is the oldest and historical grant mechanism used by the National Institute of Health. Being the most competitive grant in history, it provides funding or we can say financial support to research on various health-related subjects. The mission of the NIH is simple, to bring innovative treatments to cure life-threatening diseases.
We will get to hear more from the team of Sandrine V. Pierre about her new study on the mechanism of the Kidney and the effects of the signaling function on the human’s cardiovascular system in the coming months.