Marshall University has awarded a new research project grant. V. Pierre, Ph.D., an associate professor of biomedical sciences at the Marshall University Joan C. Edwards School of Medicine and interim director of the Marshall Institute for Interdisciplinary Research (MIIR), has been awarded a $1.36 million grant for the ongoing research program on the kidney.
This research grant is the most competitive grant issued by the National Institutes of Health.
It’s a four-year grant primarily focused on managing salt by the kidneys. The grant has been released to study and improve the existing treatments for diabetes and digestive and other known kidney-related diseases.
The regulatory mechanism of a kidney to manage salt in a body and the malfunction due to the unbalancing of salt in the body will be researched further through the newly awarded grant.
The Importance of a Kidney
We all know the importance of salt in our body and how our body removes an excessive amount of salt from the body. The imbalance of salt in our bodies causes kidney-related problems. If the amount is too high, then it may cause huge troubles in the body, resulting in damage to the kidneys.
According to a recent study, over 40% of heart-related diseases are caused by the imbalance of salt in our body, which is indirectly related to Kidneys.
The mishandling of salt balance by the body contributes to the development and progression of many common diseases, including hypertension and organ damage due to failure to remove excess salt. Therefore, the proposed investigation has profound basic and clinical implications and may provide new targets for developing better therapeutics.”
Sandrine V. Pierre, Ph.D., Associate Professor of Biomedical Sciences, Marshall University Joan C. Edwards School of Medicine
How will the Research Study Will Be Conducted?
As per the officials, Sandrine V. Pierre will begin her research project with a team of experienced researchers. The research study will be conducted at the Joan C. Edwards School of Medicine. The team will be experts in renal physiology and preclinical studies of Na/K-ATPase receptor function.
Researchers are researching new treatments that can reduce the impact of diabetes and other diseases so that they will not affect your kidneys. A recent survey shows less than 20% of kidney-related patients are referred to Nephrologists.
The medical team will study all subjects to know about the impact of medicines doctors use to cure patient infections.
The last pandemic’s severe effect damaged the myeloid cells and caused inflammation. Over 80% of patients affected by the pandemic with severe infection have lost their lives just because of Kidney or heart failure. This is what worries researchers across the globe.
Several groups have been actively working on the research program to discover the cause of this virus’s spread. This will ultimately include the mechanism of the kidney and its changes.
About Sandrine V. Pierre
Sandrine V. Pierre is the leading researcher for a new project that will conduct a deep study on the mechanism of Kidneys to manage the salt imbalance in
the kidneys. She joined Marshall University in 2014. Regarding her qualifications, she has a doctorate in cellular and molecular endocrinology from Aix-Marseille II University based in France.
She was working as a faculty at the University of Toledo College of Medicine before joining Marshall University. Her research project is based on the signaling function of the Na/K-ATPase. This project studies this signaling function’s therapeutic applications in cardiovascular diseases.
She received support from the American Heart Association and the National Heart, Lung, and Blood Institute.
About the Newly Announced R01 Grant
The R01 Grant is the oldest and historical grant mechanism used by the National Institute of Health.
As the most competitive grant in history, it provides funding or financial support to research various health-related subjects. The mission of the NIH is simple: to bring innovative treatments to cure life-threatening diseases.
We will hear more from the team of Sandrine V. Pierre about her new study on the mechanism of the Kidney and the effects of the signaling function on the human cardiovascular system in the coming months.