Current Laser Eye Surgery Clinical Trials in the US
Eyes are probably the most precious assets that we have. A world without vision is simply dark. As humans, it is not always possible to avert eye disorders and diseases or eye injuries.
In such cases, the patient needs to undergo remedying eye surgery. The success of any medical or surgical treatment depends on the way the process proved itself during the clinical trials.
Hence, today we will focus on finding the best sources where you can participate in laser eye surgery clinical trials and contribute to the advancements in eye surgery.

Laser Eye Surgery Clinical Trials
Current Laser Eye Surgery Clinical Trials in the US
Here is a list of the top laser eye surgery clinical trials in the US:
1 – The RESTORE Study, a Randomized, Controlled, Masked (Reading Center) Prospective Study
This is a “randomized, controlled, masked (reading center) prospective study of the effectiveness and safety of the ocular therapeutics dextenza (dexamethasone ophthalmic insert) 0.4 mg for the treatment of post-operative inflammation and pain in patients who have undergone PRK laser eye surgery.
The surgery is sponsored by Vance Thompson Vision in collaboration with Ocular Therapeutix, Inc.
This study aims to determine the preference of patients and outcomes of treatments with an intracanalicular dexamethasone (0.4 mg) insert as compared to the conventional steroid drop treatment method in the contralateral eye after bilateral PRK surgery.
Details of RESTORE Study
- Phase – Phase 4
- Study Type – Interventional
- Enrolment – 20 participants
For complete information and details of participation, please contact – Keeley Puls (605 – 371 – 7075) / [email protected]
2 – DEXTENZA Compared to Topical Prednisolone in Patients Undergoing Bilateral LASIK Surgery
This is a prospective, single-center, open-label, investigator-sponsored, randomized clinical study that will investigate the results for patients undergoing bilateral LASIK eye surgery through treatment with dexamethasone intracanalicular insert as compared to conventional tropical care prednisolone.
All applicants will receive eye surgery treatment.
This study aims to find outpatient preference and treatment results using intracanalicular dexamethasone (0.4 mg) insert in comparison to the conventional steroid drop treatment method in the contralateral eye after bilateral LASIK eye surgery.

Details of DEXTENZA Study
Details of DEXTENZA Study
- Phase – Phase 4
- Study Type – Interventional
- Enrolment – 20 participants
For additional details and information on this study, please contact – Sara Thiede (701 – 566 – 5390) / [email protected]
3 – Randomized, Non-inferiority Trial Comparing SMILE and LASIK
The randomized, non-inferiority trial comparing SMILE and LASIK is sponsored by the Singapore National Eye Centre.
This study is set to compare the effectiveness of SMILE (small incision lenticule extraction) eye surgery with the results obtained after undergoing LASIK (Laser In-Situ Keratomileusis) eye surgery.
The main aim of this clinical trial is to determine whether SMILE is non-inferior to LASIK regarding results after 3 months from the eye surgery.
This is a parallel-group, single tertiary center, paired-eye design, single-blinded, non-inferiority, randomized controlled trial. Participants eligible to undergo LASIK eye surgery will be enrolled in the study after expressing consent.
Details of Randomized Trial Comparing SMILE and LASIK
- Phase – Phase 4
- Study Type – Interventional
- Enrolment – 70 participants
For additional details and information, feel free to contact Donald T. Tan, FRCS (Ed.) (6562263395) / [email protected]
4 – Long-term LASIK Follow-up Study
The LASIK eye surgery method is the most commonly used treatment technique for corneal refractive surgery to treat myopia correction. This is one of the rare studies conducted to evaluate the long-term results after a LASIK eye surgery.
This study aims to assess the long-term results (after 5 to 10 years) of LASIK eye surgical treatment to determine the stability of visual outcomes and long-term effects on corneal morphology with in vivo confocal microscopy.
To be eligible for participation in this study, you must have undergone LASIK eye surgery to correct myopia or myopic astigmatism at the Kellogg Eye Center using either a femtosecond laser or microkeratome laser within the last 5 to 10 years.
Details of Long-Term LASIK Follow-up Study
- Phase – Phase 4
- Study Type – Observational
- Enrolment – 51 participants
For complete details and information on eligibility criteria and participation process, feel free to contact Kellogg Eye Center, Ann Arbor, Michigan, United States, 48105.
Conclusion
These are the current top laser eye surgery clinical trials being conducted in the US. If you want the precise details of the participation process and information on the application, feel free to use the contact details provided.
See Also
Grants for Visually Impaired Adults
Foster Grant Reading Eye Glasses
How much do clinical trials pay
References
https://clinicaltrials.gov/ct2/
I am a dedicated healthcare researcher and an enthusiast specializing in medical grants, medical education and research. Through my articles, I aim to empower healthcare professionals and researchers with valuable insights and resources to navigate these critical aspects effectively.
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