Melanoma Clinical Trials – Overview
Melanoma is the most serious type of skin cancer. It develops in the melanocytes, cells that produce melanin. This is a pigment that gives color to your skin.
Melanoma can develop in the eyes but rarely affects the body from within.
Several advances have been made in combating melanoma by scientists across the globe.
To help researchers boost their knowledge and make their studies more effective, we have listed the top melanoma clinical trials of 2022.
5 Most Popular Melanoma Clinical Trials
Here is a list of currently active melanoma clinical trials in the United States in 2022:
1 – Study to See if New Device Technology can Tell the Difference between Non-Cancer and Cancerous Melanoma
The aim of this study is to use new technology, called OTD (optical transfer diagnosis) to find whether skin lesions are non-cancer or melanomas.
This study is focused on testing the Balter Medical OTD technology to identify lesions as compared to a dermatologist.
The eligibility criteria for this clinical trial include gender, age, stage and type of disease along with previously-administered treatments or health issues.
Different studies have different guidelines to vet participants. Not every individual who is eligible and wishes to participate in the trial will be enrolled.
Hence, it is recommended to contact the research team to discuss study eligibility and potential for participation.
The inclusion criteria for this study dictate:
- Total of 300 participants in sets of 50 patients
- Over 17 years of age
- Confirmed consent
- Biopsy or excision of suspicious pigmented lesions is planned
For more details, such as the enrollment process, you can visit the official website at https://www.mayo.edu/research/clinical-trials/cls-20154259.
2 – Study Comparing Temozolomide and Selumetinib for Treating Patients with Metastatic Melanoma of the Eye
This study aims to evaluate the effectiveness of temozolomide to selumetinib for treating patients suffering from melanoma of the eye, which has also spread to other places of the body.
These drugs are often used in chemotherapy but work in different ways to halt the growth of cancerous tumor cells.
These drugs work to either kill the cancerous cells or stop them from dividing further and cease their spread. Selumetinib is likely to stop the growth of tumor cells by restricting some of the enzymes required for cell growth.
The eligibility criteria for this study are extensive. The criteria dictate that the participant must have histologically or cytologically confirmed metastatic uveal melanoma.
It must be a measurable disease and defined by at least one lesion that can be accurately measured in at least one dimension.
The life expectancy of the participant should be greater than 3 months. Besides this, there are several other strict criteria regulating participation in this study.
For more details on eligibility criteria and the application process for this clinical trial, you can visit the official website at https://www.mayo.edu/research/clinical-trials/cls-20314931.
3 – Study to Describe Patterns of Treatment, Demographics, Clinical Characteristics and Overall Survival in Patients with Unresectable or Metastatic Melanoma
The aim of this study is to describe the demographics, different patterns of patient care and clinical characteristics of patients who are suffering from unresectable or metastatic melanoma.
The duration, dosing, regimen, treatments and indication will be observed in this clinical trial.
The eligibility criteria for this study, evaluate and choose participants on the basis of age, gender, type and stage of disease as well as previous treatments or health issues.
Different studies will have different guidelines so make sure to check the relevant guidelines before applying to participate in any of these research trials.
Though there is no guarantee that every potential participant will be chosen for this trial, so it is advisable to contact the research team to know how you can improve your chances of successfully participating in this clinical trial.
For more details, you can visit the official website at https://www.mayo.edu/research/clinical-trials/cls-20212038.
4 – Study of Immune System Activity Cycles in Patients with Surgically Removed Early Stage Melanoma
This study aims to identify melanoma patients that show a pattern when their immune system is more active in fighting cancer cells. The trial will evaluate to see if treating melanoma at certain times in the cycle can be more effective.
The eligibility criteria for this trial study require participants to be at least 18 years old, with a history of early-stage malignant melanoma (Stages I, II or IIIA), a history of curative surgical reaction and willing to provide blood samples for research.
Pregnant or breastfeeding women are exempt from participating in this clinical trial.
For more information on eligibility criteria and the application process, you can visit the official website at https://www.mayo.edu/research/clinical-trials/cls-20151849.
5 – Study of Effectiveness of Stress Management Therapy for Patients with Melanoma
This study aims to test a particular stress management therapy program to check its effectiveness in reducing stress, and improving the quality of life and the immune system in patients suffering from melanoma.
The eligibility criteria for this clinical trial require participants to have a current or new diagnosis of melanoma (from stage 0 to IV), be over 18 years old, be willing to participate in all aspects of the study and provide a consent form.
As there is no guarantee that every qualifying participant will be included in the study, it is advisable to contact the research team to increase your chances of successful participation.
You may be exempt from participation in this clinical trial if you have suffered from a psychotic episode in the past 6 months or are clinically deemed acutely unstable.
To know more about eligibility criteria and participation details, you can visit the official website at https://www.mayo.edu/research/clinical-trials/cls-20204233.
There are numerous clinical trials conducted every month in different fields of medical science. Cancer research is one of the biggest and most expansive fields in medicine.
If you wish to contribute towards effective research and development of improved diagnostic, treatment and preventive measures, then you should definitely participate in a melanoma clinical trial.
You can find additional opportunities to participate in different types of melanoma clinical trials by checking the following link https://www.mayo.edu/research/clinical-trials/diseases-conditions/melanoma.
Medical Device Clinical Trials